Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression

B. Udy, Garry; P. Towers, Raewyn; G. Snell, Russell; J. Wilkins, Richard; Park, Soo-Hee; A. Ram, Prabha; J. Waxman, David; W. Davey, Helen

doi:10.1073/pnas.94.14.7239

Public

Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression

Published in Proceedings of the National Academy of Sciences • Jul 8, 1997

Authors:

Garry B. Udy

Raewyn P. Towers

Russell G. Snell

Abstract

The signal transducer and activator of transcription, STAT5b, has been implicated in signal transduction pathways for a number of cytokines and growth factors, including growth hormone (GH). Pulsatile but not continuous GH exposure activates liver STAT5b by tyrosine phosphorylation, leading to dimer...

Subject

Biology

Endocrinology

Internal medicine

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