Topical Collagen-Based Biomaterials for Chronic Wounds: Rationale and Clinical Application.

Significance: The extracellular matrix (ECM) is known to be deficient in chronic wounds. Collagen is the major protein in the ECM. Many claims are made while extolling the virtues of collagen-based biomaterials in promoting cell growth and modulating matrix metalloproteinases. This review will explo... View More