Isolation and Characterisation of a Human-Like Antibody Fragment (scFv) That Inactivates VEEV In Vitro and In Vivo

Rülker, Torsten; Voß, Luzie; Thullier, Philippe; M. O' Brien, Lyn; Pelat, Thibaut; D. Perkins, Stuart; Langermann, Claudia; Schirrmann, Thomas; Dübel, Stefan; Marschall, H.‐J.; Hust, Michael; Hülseweh, Birgit

doi:10.1371/journal.pone.0037242

Public

Isolation and Characterisation of a Human-Like Antibody Fragment (scFv) That Inactivates VEEV In Vitro and In Vivo

Published in PLoS ONE • May 30, 2012

Authors:

Torsten Rülker

Luzie Voß

Philippe Thullier

Abstract

Venezuelan equine encephalitis virus (VEEV) belongs to the Alphavirus genus and several species of this family are pathogenic to humans. The viruses are classified as potential agents of biological warfare and terrorism and sensitive detection as well as effective prophylaxis and antiviral therapies...

Subject

Alphavirus

Virology

Antibody

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