Efficacy of a Pneumococcal Conjugate Vaccine against Acute Otitis Media

Eskola, Juhani; Kilpi, Terhi; A. Palmu, Arto; Jokinen, Jukka; Eerola, Mervi; Haapakoski, Jaason; Herva, Elja; K. Takala, Aino; Käyhty, Helena; Karma, P.; Kohberger, Robert; Lockhart, Stephen; R. Siber, George; Helena Mäkelä, P.

doi:10.1056/nejm200102083440602

Public

Efficacy of a Pneumococcal Conjugate Vaccine against Acute Otitis Media

Published in New England Journal of Medicine • Feb 8, 2001

Authors:

Juhani Eskola

Terhi Kilpi

Arto A. Palmu

Abstract

BACKGROUND: Ear infections are a common cause of illness during the first two years of life. New conjugate vaccines may be able to prevent a substantial portion of cases of acute otitis media caused by Streptococcus pneumoniae. METHODS: We enrolled 1662 infants in a randomized, double-blind efficacy...

Subject

Medicine

Streptococcus pneumoniae

Otitis

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