Whole-exome SNP array identifies 15 new susceptibility loci for psoriasis.

X, Zuo; L, Sun; X, Yin; J, Gao; Y, Sheng; J, Xu; J, Zhang; C, He; Y, Qiu; G, Wen; H, Tian; X, Zheng; S, Liu; W, Wang; W, Li; Y, Cheng; L, Liu; Y, Chang; Z, Wang; Z, Li; L, Li; J, Wu; L, Fang; C, Shen; F, Zhou; B, Liang; G, Chen; H, Li; Y, Cui; A, Xu; X, Yang; F, Hao; L, Xu; X, Fan; Y, Li; R, Wu; X, Wang; X, Liu; M, Zheng; S, Song; B, Ji; H, Fang; J, Yu; Y, Sun; Y, Hui; F, Zhang; R, Yang; S, Yang; X, Zhang

doi:10.1038/ncomms7793

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Whole-exome SNP array identifies 15 new susceptibility loci for psoriasis.

Shared by NobleBlocks on Apr 9, 2015 • 12:00 AM UTC

Authors:

Zuo X

Sun L

Yin X

Abstract

Genome-wide association studies (GWASs) have reproducibly associated ∼40 susceptibility loci with psoriasis. However, the missing heritability is evident and the contributions of coding variants have not yet been systematically evaluated. Here, we present a large-scale whole-exome array analysis for...

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