Retinoids stimulate type I iodothyronine 5'-deiodinase activity in human follicular thyroid carcinoma cell lines.

Schreck, Randall; Schnieders, Frank; Schmutzler, Cornelia; Köhrle, Josef

doi:10.1210/jcem.79.3.8077363

Public

Retinoids stimulate type I iodothyronine 5'-deiodinase activity in human follicular thyroid carcinoma cell lines.

Published in The Journal of Clinical Endocrinology & Metabolism • Sep 1, 1994

Authors:

Randall Schreck

Frank Schnieders

Cornelia Schmutzler

Abstract

Iodothyronine 5'-deiodinase isoenzymes generate the thyroid hormone 3,3',5-triiodothyronine from the prohormone L-T4. Basal and retinoic acid (RA)-induced type I 5'-deiodinase (5'DI) activities were studied in human thyroid carcinoma cell lines. In the follicular thyroid carcinoma line FTC-133, nano...

Subject

Internal medicine

Endocrinology

Thyroid

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