Silver-Russell patients showing a broad range of ICR1 and ICR2 hypomethylation in different tissues.

Begemann, M; Spengler, S; Kanber, D; Haake, A; Baudis, M; Leisten, I; Binder, G; Markus, S; Rupprecht, T; Segerer, H; Fricke-Otto, S; Mühlenberg, R; Siebert, R; Buiting, K; Eggermann, T

doi:10.1111/j.1399-0004.2010.01514.x

Public

Silver-Russell patients showing a broad range of ICR1 and ICR2 hypomethylation in different tissues.

Published in Clinical genetics • Jul 1, 2011

NobleIDark:/48914/w1/20260526/A4A10945Record on NobleID

Authors:

M Begemann

,

S Spengler

,

D Kanber

Abstract

In all known congenital imprinting disorders an association with aberrant methylation or mutations at specific loci was well established. However, several patients with transient neonatal diabetes mellitus (TNDM), Silver-Russell syndrome (SRS) and Beckwith-Wiedemann syndrome (BWS) exhibiting multilo...

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