Highly purified murine interleukin 5 (IL-5) stimulates eosinophil function and prolongs in vitro survival. IL-5 as an eosinophil chemotactic factor.

Yamaguchi, Yuji; Hayashi, Yukinori; Sugama, Yasuo; Miura, Yasusada; Kasahara, Tadashi; Kitamura, Satoshi; Torisu, Motomichi; Mita, Seiji; Tominaga, A; Takatsu, Kiyoshi

doi:10.1084/jem.167.5.1737

Public

Highly purified murine interleukin 5 (IL-5) stimulates eosinophil function and prolongs in vitro survival. IL-5 as an eosinophil chemotactic factor.

Published in The Journal of Experimental Medicine • May 1, 1988

Authors:

Yuji Yamaguchi

Yukinori Hayashi

Yasuo Sugama

Abstract

The recent molecular cloning of the complementary DNA encoding T cell--replacing factor (TRF) has demonstrated that a single molecule is responsible for B cell growth factor II (BCGF-II) activity and eosinophil differentiation activity. It has been proposed that this molecule be called interleukin 5...

Subject

Eosinophil

Interleukin 5

Chemotaxis

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