Action at a Distance: Systemically Administered Adult Stem/Progenitor Cells (MSCs) Reduce Inflammatory Damage to the Cornea Without Engraftment and Primarily by Secretion of TNF-α Stimulated Gene/Protein 6

W. Roddy, Gavin; Youn Oh, Joo; Hwa Lee, Ryang; J. Bartosh, Thomas; Ylostalo, Joni; Coble, Katie; H. Rosa, Robert; J. Prockop, Darwin

doi:10.1002/stem.708

Public

Action at a Distance: Systemically Administered Adult Stem/Progenitor Cells (MSCs) Reduce Inflammatory Damage to the Cornea Without Engraftment and Primarily by Secretion of TNF-α Stimulated Gene/Protein 6

Shared by NobleBlocks on Sep 27, 2011 • 12:00 AM UTC

Authors:

Gavin W. Roddy

Joo Youn Oh

Ryang Hwa Lee

Abstract

Abstract Previous reports demonstrated that the deleterious effects of chemical injury to the cornea were ameliorated by local or systemic administration of adult stem/progenitor cells from bone marrow referred to as mesenchymal stem or stromal cells (MSCs). However, the mechanisms for the beneficia...

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