Patterns of Brain Activation in People at Risk for Alzheimer's Disease

Y. Bookheimer, Susan; H. Strojwas, Magdalena; S. Cohen, Mark; M. Saunders, Ann; A. Pericak‐Vance, Margaret; C. Mazziotta, John; W. Small, Gary

doi:10.1056/nejm200008173430701

Public

Patterns of Brain Activation in People at Risk for Alzheimer's Disease

Published in New England Journal of Medicine • Aug 17, 2000

Authors:

Susan Y. Bookheimer

Magdalena H. Strojwas

Mark S. Cohen

Abstract

BACKGROUND: The epsilon4 allele of the apolipoprotein E gene (APOE) is the chief known genetic risk factor for Alzheimer's disease, the most common cause of dementia late in life. To determine the relation between brain responses to tasks requiring memory and the genetic risk of Alzheimer's disease,...

Subject

Apolipoprotein E

Allele

Medicine

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