Comparative localization of mRNAs encoding two forms of glutamic acid decarboxylase with nonradioactive in situ hybridization methods

Esclapez, Monique; J.K. Tillakaratne, Niranjala; J. Tobin, Allan; R. Houser, Carolyn

doi:10.1002/cne.903310305

Public

Comparative localization of mRNAs encoding two forms of glutamic acid decarboxylase with nonradioactive in situ hybridization methods

Published in The Journal of Comparative Neurology • May 15, 1993

Authors:

Monique Esclapez

Niranjala J.K. Tillakaratne

Allan J. Tobin

Abstract

Nonradioactive in situ hybridization methods with digoxigenin-labeled cRNA probes were used to localize two glutamic acid decarboxylase (GAD) mRNAs in rat brain. These mRNAs encode two forms of GAD that both synthesize GABA but differ in a number of characteristics including their molecular size (65...

Subject

Glutamate decarboxylase

In situ hybridization

Biology

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