In Vitro and In Vivo Synergistic Activities of Linezolid Combined with Subinhibitory Concentrations of Imipenem against Methicillin-Resistant Staphylococcus aureus

Jacqueline, Cédric; Navas, Dominique; Batard, Éric; Miegeville, A.-F.; Le Mabecque, V.; Kerguéris, Marie-France; Bugnon, Denis; Potel, G.; Caillon, J.

doi:10.1128/aac.49.1.45-51.2005

Public

In Vitro and In Vivo Synergistic Activities of Linezolid Combined with Subinhibitory Concentrations of Imipenem against Methicillin-Resistant Staphylococcus aureus

Published in Antimicrobial Agents and Chemotherapy • Dec 23, 2004

Authors:

Cédric Jacqueline

Dominique Navas

Éric Batard

Abstract

Indifference or moderate antagonism of linezolid combined with other antibiotics in vitro and in vivo have mainly been reported in the literature. We have assessed the in vitro activities of linezolid, alone or in combination with imipenem, against methicillin-resistant Staphylococcus aureus (MRSA) ...

Subject

Linezolid

Staphylococcus aureus

Microbiology

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