A graphene quantum dot photodynamic therapy agent with high singlet oxygen generation

Ge, Jiechao; Lan, Minhuan; Zhou, Bingjiang; Liu, Weimin; Guo, Liang; Wang, Hui; Jia, Qingyan; Niu, Guangle; Huang, Xing; Zhou, Hangyue; Meng, Xiangmin; Wang, Pengfei; Lee, Chun‐Sing; Zhang, Wenjun; Han, Xiaodong

doi:10.1038/ncomms5596

Public

A graphene quantum dot photodynamic therapy agent with high singlet oxygen generation

Published in Nature Communications • Aug 8, 2014

Authors:

Jiechao Ge

Minhuan Lan

Bingjiang Zhou

Abstract

Clinical applications of current photodynamic therapy (PDT) agents are often limited by their low singlet oxygen (1O2) quantum yields, as well as by photobleaching and poor biocompatibility. Here we present a new PDT agent based on graphene quantum dots (GQDs) that can produce 1O2 via a multistate s...

Subject

Singlet oxygen

Photodynamic therapy

Photobleaching

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