Cloning and expression of a complementary DNA encoding a high affinity human neurotensin receptor.

N, Vita; P, Laurent; S, Lefort; P, Chalon; X, Dumont; M, Kaghad; D, Gully; Fur G, Le; P, Ferrara; D, Caput

doi:10.1016/0014-5793(93)81509-x

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Cloning and expression of a complementary DNA encoding a high affinity human neurotensin receptor.

Shared by NobleBlocks on Feb 1, 1993 • 12:00 AM UTC

Authors:

Vita N

Laurent P

Lefort S

Abstract

A human neurotensin receptor (hNTR) cDNA was cloned from the colonic adenocarcinoma cell line HT29. The cloned cDNA encodes a putative peptide of 418 amino acids with 7 transmembrane domains. The amino acid sequence of the hNTR is 84% identical to the rat NTR [Neuron, 4 (1990) 847-854]. Transfection...

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