Selective Inhibition of a Regulatory Subunit of Protein Phosphatase 1 Restores Proteostasis

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Shared by NobleBlocks on Apr 1, 2011 • 12:00 AM UTC

Authors:

Pavel Tsaytler

Heather P. Harding

David Ron

Abstract

Guanabenz, a small-molecule inhibitor, protects cells from lethal accrual of misfolded proteins in the endoplasmic reticulum.

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