Interleukin-22 Treatment Ameliorates Alcoholic Liver Injury in a Murine Model of Chronic-Binge Ethanol Feeding: Role of Signal Transducer and Activator of Transcription 3

Hwan Ki, Sung; Park, Oygi; Zheng, Mingquan; Morales‐Ibanez, Oriol; K. Kolls, Jay; Bataller, Ramón; Gao, Bin

doi:10.1002/hep.23837

Public

Interleukin-22 Treatment Ameliorates Alcoholic Liver Injury in a Murine Model of Chronic-Binge Ethanol Feeding: Role of Signal Transducer and Activator of Transcription 3

Published in Hepatology • Jul 16, 2010

Authors:

Sung Hwan Ki

Oygi Park

Mingquan Zheng

Abstract

UNLABELLED: Interleukin-22 (IL-22), a recently identified member of the IL-10 family of cytokines that is produced by Th17 and natural killer cells, plays an important role in controlling bacterial infection, homeostasis, and tissue repair. Here, we tested the effect of IL-22 on alcohol-induced live...

Subject

Liver injury

STAT protein

Alcoholic liver disease

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