Plasma NOV/CCN3 levels are closely associated with obesity in patients with metabolic disorders.

Pakradouni, Jihane; Le Goff, Wilfried; Calmel, Claire; Antoine, Bénédicte; Villard, Elise; Frisdal, Eric; Abifadel, Marianne; Tordjman, Joan; Poitou, Christine; Bonnefont-Rousselot, Dominique; Bittar, Randa; Bruckert, Eric; Clément, Karine; Fève, Bruno; Martinerie, Cécile; Guérin, Maryse

doi:10.1371/journal.pone.0066788

Public

Plasma NOV/CCN3 levels are closely associated with obesity in patients with metabolic disorders.

Shared by NobleBlocks on Jan 1, 2013 • 12:00 AM UTC

Authors:

Jihane Pakradouni

Wilfried Le Goff

Claire Calmel

Abstract

OBJECTIVE: Evidence points to a founder of the multifunctional CCN family, NOV/CCN3, as a circulating molecule involved in cardiac development, vascular homeostasis and inflammation. No data are available on the relationship between plasma NOV/CCN3 levels and cardiovascular risk factors in humans. T...

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