Pioglitazone, Vitamin E, or Placebo for Nonalcoholic Steatohepatitis

J. Sanyal, Arun; Chalasani, Naga; V. Kowdley, Kris; J. McCullough, Arthur; Mae Diehl, Anna; M. Bass, Nathan; A. Neuschwander‐Tetri, Brent; E. Lavine, Joel; Tonascia, James; Ünalp, Aynur; L. Van Natta, Mark; M. Clark, Jeanne; M. Brunt, Elizabeth; E. Kleiner, David; H. Hoofnagle, Jay; R. Robuck, Patricia

doi:10.1056/nejmoa0907929

Public

Pioglitazone, Vitamin E, or Placebo for Nonalcoholic Steatohepatitis

Published in New England Journal of Medicine • Apr 28, 2010

Authors:

Arun J. Sanyal

Naga Chalasani

Kris V. Kowdley

Abstract

BACKGROUND: Nonalcoholic steatohepatitis is a common liver disease that can progress to cirrhosis. Currently, there is no established treatment for this disease. METHODS: We randomly assigned 247 adults with nonalcoholic steatohepatitis and without diabetes to receive pioglitazone at a dose of 30 mg...

Subject

Nonalcoholic steatohepatitis

Pioglitazone

Medicine

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