A phase III study of radiation therapy plus carmustine with or without recombinant interferon-? in the treatment of patients with newly diagnosed high-grade glioma

C. Buckner, Jan; J. Schomberg, Paula; L. McGinnis, William; L. Cascino, Terrence; W. Scheithauer, Bernd; R. OʼFallon, Judith; F. Morton, Roscoe; A. Kuross, Steven; A. Mailliard, James; K. Hatfield, Alan; T. Cole, John; D. Steen, Preston; M. Bernath, Albert

doi:10.1002/1097-0142(20010715)92:2<420::aid-cncr1338>3.0.co;2-3

Public

A phase III study of radiation therapy plus carmustine with or without recombinant interferon-? in the treatment of patients with newly diagnosed high-grade glioma

Published in Cancer • Jan 1, 2001

Authors:

Jan C. Buckner

Paula J. Schomberg

William L. McGinnis

Abstract

BACKGROUND: The current study was conducted to determine whether the addition of interferon-alpha (IFN-alpha) to treatment with radiation therapy and carmustine (BCNU) improves time to disease progression or overall survival in patients with high-grade glioma. METHODS: Patients with anaplastic astro...

Subject

Medicine

Carmustine

Anaplastic astrocytoma

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