A phase III study of radiation therapy plus carmustine with or without recombinant interferon-alpha in the treatment of patients with newly diagnosed high-grade glioma.

JC, Buckner; PJ, Schomberg; WL, McGinnis; TL, Cascino; BW, Scheithauer; JR, O'Fallon; RF, Morton; SA, Kuross; JA, Mailliard; AK, Hatfield; JT, Cole; PD, Steen; AM, Bernath

doi:10.1002/1097-0142(20010715)92:2<420::aid-cncr1338>3.0.co;2-3

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A phase III study of radiation therapy plus carmustine with or without recombinant interferon-alpha in the treatment of patients with newly diagnosed high-grade glioma.

Shared by NobleBlocks on Jul 1, 2001 • 12:00 AM UTC

Authors:

Buckner JC

Schomberg PJ

McGinnis WL

Abstract

Background The current study was conducted to determine whether the addition of interferon-alpha (IFN-alpha) to treatment with radiation therapy and carmustine (BCNU) improves time to disease progression or overall survival in patients with high-grade glioma.Methods Patients with anaplastic astrocyt...

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