Action of DNA Repair Endonuclease ERCC1/XPF in Living Cells

B. Houtsmuller, Adriaan; Rademakers, Suzanne; L. Nigg, Alex; Hoogstraten, Deborah; H. J., Jan; , Hoeijmakers; Vermeulen, Wim

doi:10.1126/science.284.5416.958

Public

Action of DNA Repair Endonuclease ERCC1/XPF in Living Cells

Published in Science • May 7, 1999

Authors:

Adriaan B. Houtsmuller

Suzanne Rademakers

Alex L. Nigg

Abstract

To study the nuclear organization and dynamics of nucleotide excision repair (NER), the endonuclease ERCC1/XPF (for excision repair cross complementation group 1/xeroderma pigmentosum group F) was tagged with green fluorescent protein and its mobility was monitored in living Chinese hamster ovary ce...

Subject

ERCC1

Nucleotide excision repair

Xeroderma pigmentosum

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