Identification of proteins and signalling pathways involved in neoadjuvant chemotherapy responsiveness of breast tumours using proteomics

Greenwood, Christina; Alldridge, LC; Chandra Sekharan, S; Al-Janabi, K; Sauven, P; Souchelnytskyi, Serhiy

doi:10.1186/bcr2537

Public

Identification of proteins and signalling pathways involved in neoadjuvant chemotherapy responsiveness of breast tumours using proteomics

Published in Breast Cancer Research • May 1, 2010

Authors:

Christina Greenwood

LC Alldridge

S Chandra Sekharan

Abstract

A significant proportion of patients presenting with large locally advanced breast tumours, treated with neoadjuvant chemotherapy (NAC), show a poor or partial response to the treatment. The aim of this study is to identify novel phospho-proteins that may predict responsiveness to NAC treatment as t...

Subject

Surgical oncology

Breast cancer

Identification (biology)

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