The silver locus product (Silv/gp100/Pmel17) as a new tool for the analysis of melanosome transfer in human melanocyte–keratinocyte co‐culture

K. Singh, Suman; Nizard, Carine; Kurfurst, Robin; Bonte, Frederic; Schnebert, Sylvianne; J. Tobin, Desmond

doi:10.1111/j.1600-0625.2008.00702.x

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The silver locus product (Silv/gp100/Pmel17) as a new tool for the analysis of melanosome transfer in human melanocyte–keratinocyte co‐culture

Shared by NobleBlocks on Apr 7, 2008 • 12:00 AM UTC

Authors:

Suman K. Singh

Carine Nizard

Robin Kurfurst

Abstract

Abstract: Melanosomes are melanocyte‐specific lysosome‐related organelles that are transferred to keratinocytes of the epidermis and anagen hair bulb. Transferred melanin forms supra‐nuclear caps that protect epidermal keratinocytes against UV irradiation. The mechanism(s) responsible for melanosome...

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