Intraocular pressure reduction and neuroprotection conferred by bone marrow-derived mesenchymal stem cells in an animal model of glaucoma

Roubeix, Christophe; Godefroy, David; Mias, Céline; Sapienza, Anaïs; Riancho, Luisa; Dégardin, Julie; Fradot, Valérie; Ivković, Ivana; Picaud, Serge; Sennlaub, Florian; Denoyer, Alexandre; Rostène, William; Sahel, José‐Alain; Melik Parsadaniantz, Stéphane; Brignole‐Baudouin, Françoise; Baudouin, Christophe

doi:10.1186/s13287-015-0168-0

Public

Intraocular pressure reduction and neuroprotection conferred by bone marrow-derived mesenchymal stem cells in an animal model of glaucoma

Published in Stem Cell Research & Therapy • Sep 16, 2015

Authors:

Christophe Roubeix

David Godefroy

Céline Mias

Abstract

INTRODUCTION: Glaucoma is a sight-threatening retinal neuropathy associated with elevated intraocular pressure (IOP) due to degeneration and fibrosis of the trabecular meshwork (TM). Glaucoma medications aim to reduce IOP without targeting the specific TM pathology, Bone-marrow mesenchymal stem cell...

Subject

Mesenchymal stem cell

Stem cell

Glaucoma

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