Meganuclease-mediated Inhibition of HSV1 Infection in Cultured Cells.

S, Grosse; N, Huot; C, Mahiet; S, Arnould; S, Barradeau; DL, Clerre; I, Chion-Sotinel; C, Jacqmarcq; B, Chapellier; A, Ergani; C, Desseaux; F, Cédrone; E, Conseiller; F, Pâques; M, Labetoulle; J, Smith

doi:10.1038/mt.2010.302

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Meganuclease-mediated Inhibition of HSV1 Infection in Cultured Cells.

Shared by NobleBlocks on Jan 11, 2011 • 12:00 AM UTC

Authors:

Grosse S

Huot N

Mahiet C

Abstract

Herpes simplex virus type 1 (HSV1) is a major health problem. As for most viral diseases, current antiviral treatments are based on the inhibition of viral replication once it has already started. As a consequence, they impair neither the viral cycle at its early stages nor the latent form of the vi...

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