Common patterns and disease-related signatures in tuberculosis and sarcoidosis

Maertzdorf, Jeroen; Weiner, January; Mollenkopf, Hans‐Joachim; Accelerating Medicines Partnership in RA SLE Network, T.; Bauer, Torsten; Prasse, Antje; Müller–Quernheim, Joachim; H. E. Kaufmann, Stefan; Bellinger, Oswald; Diel, Roland; Ehlers, Stefan; Heykes-Uden, H; Hölscher, Christoph; H. E. Kaufmann, Stefan; Lange, Christoph; G. Meyer, Christian; Niemann, Stefan; Nöthlings, Ute; Reiling, Norbert; Schaberg, Tom; Stenger, Steffen

doi:10.1073/pnas.1121072109

Public

Common patterns and disease-related signatures in tuberculosis and sarcoidosis

Published in Proceedings of the National Academy of Sciences • Apr 30, 2012

Authors:

Jeroen Maertzdorf

January Weiner

Hans‐Joachim Mollenkopf

Abstract

In light of the marked global health impact of tuberculosis (TB), strong focus has been on identifying biosignatures. Gene expression profiles in blood cells identified so far are indicative of a persistent activation of the immune system and chronic inflammatory pathology in active TB. Definition o...

Subject

Proinflammatory cytokine

Immunology

Tuberculosis

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