Corticotropin-releasing hormone and oxytocin stimulate the release of placental proopiomelanocortin peptides.

AN, Margioris; M, Grino; P, Protos; PW, Gold; GP, Chrousos

doi:10.1210/jcem-66-5-922

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Corticotropin-releasing hormone and oxytocin stimulate the release of placental proopiomelanocortin peptides.

Shared by NobleBlocks on May 1, 1988 • 12:00 AM UTC

Authors:

Margioris AN

Grino M

Protos P

Abstract

Human placenta contains the POMC-derived peptides ACTH, alpha MSH, and beta-endorphin, and CRH. High concentrations of immunoreactive (IR) CRH have been recently demonstrated in maternal plasma during pregnancy. To determine if the human placenta secretes CRH and POMC-derived peptides, we developed ...

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