Late HDV RNA Relapse After Peginterferon Alpha-Based Therapy of Chronic Hepatitis Delta

Heidrich, Benjamin; Yurdaydın, Cihan; Kabaçam, Gökhan; A. Ratsch, Boris; Zachou, Kalliopi; Bremer, Birgit; Ν. Dalekos, George; Erhardt, Andreas; Tabak, Fehmı; Yalçın, Kendal; Gürel, Selım; Zeuzem, Stefan; Cornberg, Markus; Bock, C.–Thomas; P. Manns, Michael; Wedemeyer, Heiner

doi:10.1002/hep.27102

Public

Late HDV RNA Relapse After Peginterferon Alpha-Based Therapy of Chronic Hepatitis Delta

Published in Hepatology • Feb 28, 2014

Authors:

Benjamin Heidrich

Cihan Yurdaydın

Gökhan Kabaçam

Abstract

UNLABELLED: Interferon alpha is the only treatment option for hepatitis delta virus (HDV). Trials investigating the efficacy of pegylated interferon alpha (PEG-IFNa) showed HDV RNA negativity rates of 25-30% 24 weeks after therapy. However, the clinical and virological long-term outcome of HDV-infec...

Subject

Medicine

Adefovir

Internal medicine

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