Role of Class A Penicillin-Binding Proteins in the Expression of β-Lactam Resistance in <i>Enterococcus faecium</i>

B. Rice, Louis; L. Carias, Lenore; D. Rudin, Susan; A. Hutton, Rebecca; H. Marshall, Steven; O. Hassan, Medhat; Josseaume, Nathalie; Dubost, Lionel; Marie, Arul; Arthur, Michel

doi:10.1128/jb.01834-08

Public

Role of Class A Penicillin-Binding Proteins in the Expression of β-Lactam Resistance in Enterococcus faecium

Published in Journal of Bacteriology • Mar 21, 2009

Authors:

Louis B. Rice

Lenore L. Carias

Susan D. Rudin

Abstract

Peptidoglycan is polymerized by monofunctional d,d-transpeptidases belonging to class B penicillin-binding proteins (PBPs) and monofunctional glycosyltransferases and by bifunctional enzymes that combine both activities (class A PBPs). Three genes encoding putative class A PBPs (pbpF, pbpZ, and ponA...

Subject

Peptidoglycan

Penicillin binding proteins

Biology

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