Gastrointestinal transit, release and plasma pharmacokinetics of a new oral budesonide formulation

Brunner, Martin; Ziegler, S.; F. D. Di Stefano, Andrea; Dehghanyar, Pejman; Kletter, Kurt; Tschurlovits, M.; Edoardo Villa, Roberto; Bozzella, Roberta; Celasco, Giuseppe; Moro, L.; Rusca, Antonio; Dudczak, Robert; Müller, M.

doi:10.1111/j.1365-2125.2005.02517.x

Public

Gastrointestinal transit, release and plasma pharmacokinetics of a new oral budesonide formulation

Published in British Journal of Clinical Pharmacology • Sep 27, 2005

Authors:

Martin Brunner

S. Ziegler

Andrea F. D. Di Stefano

Abstract

AIMS: The aims of the study were to: (1) evaluate the gastrointestinal transit, release and absorption of budesonide from tablets with a new multimatrix formulation (MMX) designed to release the drug throughout the whole colon, and (2) assess the influence of food on budesonide bioavailability. METH...

Subject

Bioavailability

Pharmacokinetics

Budesonide

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