Leptin Is an Endogenous Protective Protein against the Toxicity Exerted by Tumor Necrosis Factor

Tumor necrosis factor (TNF) is a central mediator of a number of important pathologies such as the systemic inflammatory response syndrome. Administration of high TNF doses induces acute anorexia, metabolic derangement, inflammation, and eventually shock and death. The in vivo effects of TNF are lar... View More