Processing and Localization of ADAMTS-1 and Proteolytic Cleavage of Versican during Cumulus Matrix Expansion and Ovulation

L. Russell, Darryl; M. H. Doyle, Kari; A. Ochsner, Scott; D. Sandy, John; S. Richards, JoAnne

doi:10.1074/jbc.m300519200

Public

Processing and Localization of ADAMTS-1 and Proteolytic Cleavage of Versican during Cumulus Matrix Expansion and Ovulation

Published in Journal of Biological Chemistry • Oct 1, 2003

Authors:

Darryl L. Russell

Kari M. H. Doyle

Scott A. Ochsner

Abstract

ADAMTS-1 (a disintegrin and metalloprotease with thrombospondin motifs-1) is a member of the ADAMTS family of metalloproteases which, together with ADAMTS-4 and ADAMTS-5, has been shown to degrade members of the lectican family of proteoglycans. ADAMTS-1 mRNA is induced in granulosa cells of periovu...

Subject

Versican

ADAMTS

Cleavage (geology)

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