Free fatty acids in obesity and type 2 diabetes: defining their role in the development of insulin resistance and β‐cell dysfunction

Boden, G.; I. Shulman, Gerald

doi:10.1046/j.1365-2362.32.s3.3.x

Public

Free fatty acids in obesity and type 2 diabetes: defining their role in the development of insulin resistance and β‐cell dysfunction

Published in European Journal of Clinical Investigation • May 16, 2002

Authors:

G. Boden

Gerald I. Shulman

Abstract

Plasma free fatty acids (FFA) play important physiological roles in skeletal muscle, heart, liver and pancreas. However, chronically elevated plasma FFA appear to have pathophysiological consequences. Elevated FFA concentrations are linked with the onset of peripheral and hepatic insulin resistance ...

Subject

Internal medicine

Endocrinology

Insulin resistance

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