Increased expression and cellular localization of inducible nitric oxide synthase and cyclooxygenase 2 in Helicobacter pylori gastritis☆, ☆☆

Man Fu, Shu; Ramanujam, Krishnan; S. Y. Wong, April; T. Fantry, George; B. Drachenberg, Cinthia; James, Sian; J Meltzer, S; T. Wilson, Keith

doi:10.1016/s0016-5085(99)70496-8

Public

Increased expression and cellular localization of inducible nitric oxide synthase and cyclooxygenase 2 in Helicobacter pylori gastritis☆, ☆☆

Published in Gastroenterology • Jun 1, 1999

Authors:

Shu Man Fu

Krishnan Ramanujam

April S. Y. Wong

Abstract

BACKGROUND & AIMS: Inducible nitric oxide synthase (iNOS) and cyclooxygenase (COX)-2 are important regulators of mucosal inflammation and epithelial cell growth. To determine the role of iNOS and COX-2 in Helicobacter pylori-induced tissue injury, we compared their gene expression in H. pylori-induc...

Subject

Lamina propria

Gastritis

Nitric oxide synthase

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