Tumour suppressors miR-1 and miR-133a target the oncogenic function of purine nucleoside phosphorylase (PNP) in prostate cancer

Kojima, Satoko; Chiyomaru, Takeshi; Kawakami, Kazumori; Yoshino, Hirofumi; Enokida, Hideki; Nohata, Nijiro; Fuse, M; Ichikawa, Tomohiko; Naya, Yukio; Nakagawa, Masayuki; Seki, Naohiko

doi:10.1038/bjc.2011.462

Public

Tumour suppressors miR-1 and miR-133a target the oncogenic function of purine nucleoside phosphorylase (PNP) in prostate cancer

Published in British Journal of Cancer • Nov 8, 2011

Authors:

Satoko Kojima

Takeshi Chiyomaru

Kazumori Kawakami

Abstract

BACKGROUND: Our recent analyses of miRNA expression signatures showed that miR-1 and miR-133a were significantly reduced in several types of cancer. Interestingly, miR-1 and miR-133a are located on the same chromosomal locus in the human genome. We examined the functional significance of miR-1 and m...

Subject

DU145

Biology

Carcinogenesis

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