Abnormally increased endothelin-1 in plasma during the night in obstructive sleep apnea: relation to blood pressure and severity of disease.

PH, Gjørup; L, Sadauskiene; J, Wessels; O, Nyvad; B, Strunge; EB, Pedersen

doi:10.1016/j.amjhyper.2006.05.021

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Abnormally increased endothelin-1 in plasma during the night in obstructive sleep apnea: relation to blood pressure and severity of disease.

Shared by NobleBlocks on Jan 1, 2007 • 12:00 AM UTC

Authors:

Gjørup PH

Sadauskiene L

Wessels J

Abstract

Background The mechanisms involved in development and maintenance of hypertension in obstructive sleep apnea (OSA) are not clarified. We hypothesize that patients with OSA have an abnormal nocturnal level of some vasoactive hormones during the night.Methods We studied 32 patients with OSA and 19 hea...

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