Irbesartan in Patients with Heart Failure and Preserved Ejection Fraction

M. Massie, Barry; E. Carson, Peter; J.V. McMurray, John; Komajda, Michel; S. McKelvie, Robert; R. Zile, Michael; Anderson, Susan; Donovan, Mark; Iverson, Erik; Staiger, C; Ptaszynska, Agata

doi:10.1056/nejmoa0805450

Public

Irbesartan in Patients with Heart Failure and Preserved Ejection Fraction

Published in New England Journal of Medicine • Nov 11, 2008

Authors:

Barry M. Massie

Peter E. Carson

John J.V. McMurray

Abstract

BACKGROUND: Approximately 50% of patients with heart failure have a left ventricular ejection fraction of at least 45%, but no therapies have been shown to improve the outcome of these patients. Therefore, we studied the effects of irbesartan in patients with this syndrome. METHODS: We enrolled 4128...

Subject

Irbesartan

Medicine

Hazard ratio

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