Global Gene Expression Profiling of a Population Exposed to a Range of Benzene Levels

M. McHale, Cliona; Zhang, Luoping; Lan, Qing; Vermeulen, Roel; Li, Guilan; Hubbard, Alan; E. Porter, Kristin; Thomas, Reuben; J. Portier, Christopher; Shen, Min; M. Rappaport, Stephen; Yin, Songnian; T. Smith, Martyn; Rothman, Nathaniel

doi:10.1289/ehp.1002546

Public

Global Gene Expression Profiling of a Population Exposed to a Range of Benzene Levels

Published in Environmental Health Perspectives • Dec 14, 2010

Authors:

Cliona M. McHale

Luoping Zhang

Qing Lan

Abstract

BACKGROUND: Benzene, an established cause of acute myeloid leukemia (AML), may also cause one or more lymphoid malignancies in humans. Previously, we identified genes and pathways associated with exposure to high (> 10 ppm) levels of benzene through transcriptomic analyses of blood cells from a smal...

Subject

Leukemia

Confounding

Biomarker

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