Strategic advantages of insulin-like growth factor-I expression for cardioprotection.

W, Chao; T, Matsui; MS, Novikov; J, Tao; L, Li; H, Liu; Y, Ahn; A, Rosenzweig

doi:10.1002/jgm.347

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Strategic advantages of insulin-like growth factor-I expression for cardioprotection.

Shared by NobleBlocks on Apr 1, 2003 • 12:00 AM UTC

Authors:

Chao W

Matsui T

Novikov MS

Abstract

Background Insulin-like growth factor-I (IGF-I) peptide has beneficial effects on cardiomyocyte function and survival, many of which are mediated through the serine-threonine kinase, Akt. However, concerns about systemic effects of IGF-I peptide limit its clinical application. The present study test...

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