Effect of Nesiritide in Patients with Acute Decompensated Heart Failure

O’Connor, Cathal; C. Starling, Randall; F. Hernandez, Adrian; W. Armstrong, Paul; Dickstein, Kenneth; Hasselblad, Vic; Heizer, Gretchen; Komajda, Michel; M. Massie, Barry; J.V. McMurray, John; S. Nieminen, Markku; J. Reist, Craig; L. Rouleau, Jean; Swedberg, Karl; F. Adams, Kirkwood; D. Anker, Stefan; Atar, Dan; Battler, A; Botero, Rodrigo; R. Bohidar, N.; Butler, Javed; Clausell, Nadine; Corbalán, Ramón; Rosa Costanzo, Maria; Dahlström, Ulf; I. Deckelbaum, Lawrence; Díaz, Rafael; E. Dunlap, Mark; A. Ezekowitz, Justin; Bruce Feldman, DO; Michael Felker, G.; C. Fonarow, Gregg; Gennevois, Daniel; S. Gottlieb, Stephen; A. Hill, James; E. Hollander, Judd; G. Howlett, Jonathan; Hudson, Michael; D. Kociol, Robb; Krum, Henry; Laucevičius, Aleksandras; C. Levy, Wayne; Méndez, Gustavo; Metra, Marco; Mittal, Sanjay; Oh, Byung‐Hee; L. Pereira, Naveen; Ponikowski, Piotr; Wilson Tang, W.H.; Tanomsup, Supachai; R. Teerlink, John; Triposkiadis, F.; W. Troughton, Richard; A. Voors, Adriaan; J. Whellan, David; Zannad, Faı̈ez; M. Califf, Robert

doi:10.1056/nejmoa1100171

Public

Effect of Nesiritide in Patients with Acute Decompensated Heart Failure

Published in New England Journal of Medicine • Jul 6, 2011

Authors:

Cathal O’Connor

Randall C. Starling

Adrian F. Hernandez

Abstract

BACKGROUND: Nesiritide is approved in the United States for early relief of dyspnea in patients with acute heart failure. Previous meta-analyses have raised questions regarding renal toxicity and the mortality associated with this agent. METHODS: We randomly assigned 7141 patients who were hospitali...

Subject

Nesiritide

Medicine

Heart failure

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