MiRNA-Directed Regulation of VEGF and Other Angiogenic Factors under Hypoxia

Zhong, Hua; Lv, Qing; Ye, Wenbin; Amy Wong, Chung-Kwun; Cai, Guoping; Gu, Dayong; Ji, Yanhong; Zhao, Chen; Wang, Jifeng; B. Yang, Burton; Zhang, Yaou

doi:10.1371/journal.pone.0000116

Public

MiRNA-Directed Regulation of VEGF and Other Angiogenic Factors under Hypoxia

Published in PLoS ONE • Dec 27, 2006

Authors:

Hua Zhong

Qing Lv

Wenbin Ye

Abstract

MicroRNAs (miRNAs) are a class of 20-24 nt non-coding RNAs that regulate gene expression primarily through post-transcriptional repression or mRNA degradation in a sequence-specific manner. The roles of miRNAs are just beginning to be understood, but the study of miRNA function has been limited by p...

Subject

microRNA

Biology

Regulation of gene expression

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