Detection of Recent HIV-1 Infection Using a New Limiting-Antigen Avidity Assay: Potential for HIV-1 Incidence Estimates and Avidity Maturation Studies

T. Duong, Yen; Qiu, Maofeng; K. De, Anindya; Jackson, Keisha; Dobbs, Trudy; A. Kim, Andrea; N. Nkengasong, John; Parekh, Bharat

doi:10.1371/journal.pone.0033328

Public

Detection of Recent HIV-1 Infection Using a New Limiting-Antigen Avidity Assay: Potential for HIV-1 Incidence Estimates and Avidity Maturation Studies

Published in PLoS ONE • Mar 27, 2012

Authors:

Yen T. Duong

Maofeng Qiu

Anindya K. De

Abstract

BACKGROUND: Accurate and reliable laboratory methods are needed for estimation of HIV-1 incidence to identify the high-risk populations and target and monitor prevention efforts. We previously described a single-well limiting-antigen avidity enzyme immunoassay (LAg-Avidity EIA) to detect recent HIV-...

Subject

Avidity

Immunoassay

Serology

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