THE INFLUENCE OF ORALLY ADMINISTERED ALKALI AND ACID ON THE RENAL EXCRETION OF QUINACRINE, CHLOROQUINE AND SANTOQUINE 1

Haag and Larson (1) demonstrated in 1942 that in the case of nicotine the extent of urinary ex- cretion of a chemical may be related to the reac- tion of urine. They emphasized the importance of taking into consideration the dissociation con- stant of a drug and the relative reabsorbability of the f... View More