Redox Regulation of Fos and Jun DNA-Binding Activity in Vitro

Abate, Cory; Patel, Lekha; J. Rauscher, Frank; Curran, Tom

doi:10.1126/science.2118682

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Redox Regulation of Fos and Jun DNA-Binding Activity in Vitro

Shared by NobleBlocks on Sep 7, 1990 • 12:00 AM UTC

Authors:

Cory Abate

Lekha Patel

Frank J. Rauscher

Abstract

The proto-oncogenes c- fos and c- jun function cooperatively as inducible transcription factors in signal transduction processes. Their protein products, Fos and Jun, form a heterodimeric complex that interacts with the DNA regulatory element known as the activator protein-1 (AP-1) binding site. Dim...

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