The phosphoinositide 3-kinase pathway.
Published in Science (New York, N.Y.) • May 31, 2002
Authors:
Lewis C Cantley
Abstract
Phosphorylated lipids are produced at cellular membranes during signaling events and contribute to the recruitment and activation of various signaling components. The role of phosphoinositide 3-kinase (PI3K), which catalyzes the production of phosphatidylinositol-3,4,5-trisphosphate, in cell surviva...
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