Pathogens Penetrating the Central Nervous System: Infection Pathways and the Cellular and Molecular Mechanisms of Invasion

J. Dando, Samantha; Mackay‐Sim, Alan; Norton, Robert; J. Currie, Bart; A. St John, James; Ekberg, Jenny; R. Batzloff, Michael; C. Ulett, Glen; R. Beacham, Ifor

doi:10.1128/cmr.00118-13

Public

Pathogens Penetrating the Central Nervous System: Infection Pathways and the Cellular and Molecular Mechanisms of Invasion

Published in Clinical Microbiology Reviews • Oct 1, 2014

Authors:

Samantha J. Dando

Alan Mackay‐Sim

Robert Norton

Abstract

The brain is well protected against microbial invasion by cellular barriers, such as the blood-brain barrier (BBB) and the blood-cerebrospinal fluid barrier (BCSFB). In addition, cells within the central nervous system (CNS) are capable of producing an immune response against invading pathogens. Non...

Subject

Burkholderia pseudomallei

Biology

Central nervous system

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