Clinical Trial of Lamivudine in Children with Chronic Hepatitis B

M. Jonas, Maureen; A. Kelley, Deirdre; Mizerski, J.; Badía, Isabel; Areias, Jorge; B. Schwarz, Kathleen; Little, Nancy; Greensmith, Martin; D. Gardner, Stephen; Steve Bell, M.; Sokal, Étienne

doi:10.1056/nejmoa012452

Public

Clinical Trial of Lamivudine in Children with Chronic Hepatitis B

Published in New England Journal of Medicine • May 30, 2002

Authors:

Maureen M. Jonas

Deirdre A. Kelley

J. Mizerski

Abstract

BACKGROUND: Lamivudine therapy is effective for chronic hepatitis B infection in adults. We evaluated the efficacy and tolerability of lamivudine as a treatment for chronic infection with hepatitis B virus (HBV) in children. METHODS: Children with chronic hepatitis B were randomly assigned in a 2:1 ...

Subject

Lamivudine

Medicine

Seroconversion

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