Ratios of activated matrix metalloproteinase‐9 to tissue inhibitor of matrix metalloproteinase‐1 in wound fluids are inversely correlated with healing of pressure ulcers

P. LADWIG, GLENN; C. Robson, Martin; Liu, Ran; Ann Kuhn, M.; Muir, David; S. Schultz, Gregory

doi:10.1046/j.1524-475x.2002.10903.x

Public

Ratios of activated matrix metalloproteinase‐9 to tissue inhibitor of matrix metalloproteinase‐1 in wound fluids are inversely correlated with healing of pressure ulcers

Published in Wound Repair and Regeneration • Jan 1, 2002

Authors:

GLENN P. LADWIG

Martin C. Robson

Ran Liu

Abstract

Previous analyses of fluids collected from chronic, nonhealing wounds found elevated levels of inflammatory cytokines, elevated levels of proteinases, and low levels of growth factor activity compared with fluids collected from acute, healing wounds. This led to the general hypothesis that chronic i...

Subject

Matrix metalloproteinase

Wound healing

Medicine

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