Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting

P. B. Wiklander, Oscar; Z. Nordin, Joel; J. O’Loughlin, Aisling; Gustafsson, Ylva; Corso, Giulia; Mäger, Imre; Vader, Pieter; Lee, Yi; Sork, Helena; Seow, Yiqi; Heldring, Nina; Alvarez‐Erviti, Lydia; Edvard Smith, CI; Le Blanc, Katarina; Macchiarini, Paolo; Jungebluth, Philipp; J. A. Wood, Matthew; EL Andaloussi, Samir

doi:10.3402/jev.v4.26316

Public

Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting

Published in Journal of Extracellular Vesicles • Jan 1, 2015

Authors:

Oscar P. B. Wiklander

Joel Z. Nordin

Aisling J. O’Loughlin

Abstract

Extracellular vesicles (EVs) have emerged as important mediators of intercellular communication in a diverse range of biological processes. For future therapeutic applications and for EV biology research in general, understanding the in vivo fate of EVs is of utmost importance. Here we studied biodi...

Subject

Biodistribution

In vivo

Spleen

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