Heat Shock Proteins 27 and 70: Anti-Apoptotic Proteins with Tumorigenic Properties

Garrido, Carmen; Brunet, Mathilde; Didelot, Celine; Zermati, Yaël; Schmitt, E.; Kroemer, Guido

doi:10.4161/cc.5.22.3448

Public

Heat Shock Proteins 27 and 70: Anti-Apoptotic Proteins with Tumorigenic Properties

Published in Cell Cycle • Nov 2, 2006

Authors:

Carmen Garrido

Mathilde Brunet

Celine Didelot

Abstract

Heat shock proteins (HSP) HSP27 and HSP70 are expressed in response to a wide variety of physiological and environmental insults including anticancer chemotherapy, thus allowing the cell to survive to lethal conditions. Several mechanisms account for the cytoprotective effect of HSP27 and HSP70. (1)...

Subject

Hsp27

Biology

Heat shock protein

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