Antiproliferative and Apoptotic Effects of Tocopherols and Tocotrienols on Preneoplastic and Neoplastic Mouse Mammary Epithelial Cells

Mcintyre, Barry; P. Briski, Karen; Gapor, Abdul; W. Sylvester, Paul

doi:10.1046/j.1525-1373.2000.22434.x

Public

Antiproliferative and Apoptotic Effects of Tocopherols and Tocotrienols on Preneoplastic and Neoplastic Mouse Mammary Epithelial Cells

Published in Proceedings of The Society for Experimental Biology and Medicine • Sep 1, 2000

Authors:

Barry Mcintyre

Karen P. Briski

Abdul Gapor

Abstract

Studies were conducted to determine the comparative effects of tocopherols and tocotrienols on preneoplastic (CL-S1), neoplastic (-SA), and highly malignant (+SA) mouse mammary epithelial cell growth and viability in vitro. Over a 5-day culture period, treatment with 0-120 microM alpha- and gamma-to...

Subject

Tocotrienol

Apoptosis

Vitamin E

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